reddit alpha lipoic acid

(v) Selenium is an important essential element, that is present at a broad range of levels across populations. I've been doing some reading on ALA supplementation (Alpha Lipoic Acid, not to be confused with Alpha Lineolic Acid for Omega-3 supplementation). Without Alpha-lipoic acid, free radicals will form a chemical reaction that can lead to the emergence of diseases, such as stroke. Lipoic acid, also known as Alpha-Lipoic acid, (ALA, Thioctic acid) is similar in structure and function to a vitamin. But, there are few studies that refer to protective effects and potential mechanisms on traumatic brain injury (TBI). Frequent, low-dose Lipoic Acid in accordance with half-life, makes sense from a chelation perspective, especially so for lipoic acid given its relatively lower affinity for heavy metals compared to stronger chelators. Much higher doses for way longer periods of time and saw no change. Alpha-lipoic acid or ALA is a naturally occurring compound that's made in the body. Glutathione is an important physiological chelator, and the reduced form of glutathione protects cells from reactive oxygen species (ROS) associated with heavy metals [58, 59, 60, 61]. Symptoms: chronic sleep-maintenance insomnia (frequent (2-5) awakenings and low sleep time (avg 5.5hr rg 3-7hr), fatigue, brain fog, depression, anxiety, History: previously heavy fish diet with periods of >3 cans of tuna per week. reddit. https://www.amazon.com/R-Alpha-Lipoic-R-LIPOIC-count-STRENGTH/dp/B01M0QS5C7, There are many studies on its effectiveness available on the pubmed site. Despite that fact, there has been a lot of recent interest in using ALA supplements. 5) Acetyl L-Carnitine and Alpha Lipoic Acid Price. In accordance with the serotonin theory of depression, it may be possible to treat depression by increasing insulin activity. ALA is also beneficial in combating damages and infections that attack vital organs. A subreddit for those living with neuropathy. It is widely understood that alpha lipoic acid is manufactured endogenously within the human body and that its presence is essential for aerobic metabolism, or the means by which the body generates energy via breakdown of carbohydrates, amino … (i) Dietary fibers from various food products, including bran from grains, as well as fruit, have been evaluated as an alternative or adjunct to chelation therapy, with the aim to interrupt enterohepatic recirculation [34, 35, 36], and to modulate intestinal flora [37], with findings of reduced levels of mercury in the brain and blood. Look do your research on it! ReddIt. Alpha‐lipoic acid (ALA) is a naturally occurring dithiol micronutrient which acts as a cofactor for mitochondrial enzyme activity. Optim-ALA Optimized Alpha Lipoic Acid is a highly bioavailable alpha lipoic acid supplement from Natrium Health, the sister company of Nootropics Depot. Simply Nature's Pure Alpha Lipoic Acid RLA R-LA R-Lipoic S-Lipoic HIGHEST Quality ALA, Better Bioavailability also known as Thioctic Acid 120 Count 4 Month Supply. Garlic prevented cadmium-induced kidney damage [44] and decreased the oxidative damage due to lead in rats [45]. "This may explain why the results of trials are confusing.I'm going to have to change when I take mine. Clinical experience is that it must be used carefully as it poses particular risks of redistribution of metals. Lipoic acid also prevents diabetic neuropathy characterized by pain, burning, and stabbing sensations in the extremities. Alpha-lipoic acid is essential for certain enzymatic reactions, but there is no official recommended dietary intake of ALA . Metal-binding proteins, including metallothioneins, are potent chelators for heavy metals and are central to the natural response of the body to these toxic elements [27, 28]. A year ago my mother started suffering from some pretty obvious, and worrying memory loss. CDN$ 5.54 shipping. (iv) Cilantro (leaves of Coriandrum sativum), a popular culinary and medicinal herb, gained attention when a soup was reported to enhance mercury excretion following dental amalgam removal, and its use as a chelator remains popular despite limited evidence [46]. CDN$ 35.99 CDN$ 35. Because it protects the endothelium, alpha lipoic acid reduces the risk of diabetic vascular disease and kidney disease. Alpha-lipoic acid has been used in alternative medicine as a possibly effective aid in weight loss, treating diabetic nerve pain, healing wounds, lowering blood sugar, improving skin discoloration caused by vitiligo, and decreasing complications of coronary artery bypass graft (CABG) surgery. When looking up information about this to gather case studies/evidence/etc. Tried on and off twice. * On a lark I decided to google "alpha lipoic acid and multiple sclerosis," and sure enough, there's some early research indicating that it reduced the speed of brain volume loss in people with secondary progressive MS by 68%. Nothing else has helped other than narcotic pain meds or Neurontin, many years ago until the nasty side effects set it and became unable to take any of those drugs. After some research, I suggested she try taking the maximum recommended dose of alpha lipoic acid, which is an antioxidant that affects the brain. Modified citrus pectin plus alginate products have been used successfully to reduce lead and mercury in case studies [39]. Alpha‐lipoic acid (LA), a potent antioxidant, has been shown to be an effective treatment for diabetic neuropathy when given intravenously. Given the literature value, dosing according to Cutler Therapy would result in fluctuating between just over 100% and 1% blood levels, obviously suboptimal (and also below the clinical determination for elimination). On the face of it, selenide might not be compatible with chelation, as the two agents may counter the effectiveness of one another [62]; however, selenium may be incorporated in organic molecules, and organic selenium/mercury complexes may be transported through membranes. In animals, it decreased lead absorption into bone, and inhibited the action of the delta-aminolevulinic acid dehydratase (ALAD) enzyme [47]. Due to its potential antioxidant activity, … Studies show it may help with symptoms of diabetes, cancer treatments, and other conditions. They are rich in membranes, particularly of excitable tissues, and they decrease oxidative stress markers resulting from heavy metal exposure. Alpha-lipoic acid is an organic compound found in all human cells. It serves vital functions at the cellular level, such as energy production. Has anyone else tried this for neuropathy? It may be administered intravenously, in creams, and via nebulizer. Alpha-lipoic acid is a natural protective antioxidant. Lipoic acid (LA), also known as alpha-lipoic acid (ALA), R-lipoic acid, or thioctic acid, is a disulfide-containing compound , found inside every cell of the body . Good luck! In humans, organic selenium supplementation was beneficial in a controlled trial among 103 mercury-exposed villagers [63]. Discussion of nootropics and cognitive enhancers. Worth the try though i suppose. But lipoic acid declines in your body as you age. Much of the research involving alpha-lipoic acid has been centered on the prevention of diabetes and the management of diabetic nerve pain. for evidence-based support, only the Cutler Therapy comes up. Acetyl L-Carnitine and Alpha Lipoic Acid is sold by bottles of 60 capsules, containing 650 mg. Has anyone else tried this for neuropathy? If you have confirmed that you have mercury toxicity, get a real chelating agent, preferably one actually backed by clinical evidence, and don't try an unproven treatment that doesn't sound likely to work and could be harmful. Alpha-lipoic acid is a natural antioxidant that can be found in potatoes, spinach, broccoli, liver, kidney, and yeast. It’s made inside the mitochondrion — also known as the powerhouse of cells — where it … * It has important characteristics that contribute to liver, nerve, and eye health. Therefore, the nutrient alpha lipoic acid should be clinically tested … In this work, a comparative assessment of the effect of drugs (diazepam, phenibut and its isomers, hopantenic acid, pyritinol, piracetam and Phenotropil) on the indicators of stress-reaction of animals in three models of experimental stress, which received the … Several supplements are also in use to address metal toxicities. Advocates of ALA make claims that range from beneficial effects for treating conditions such as diabetes and HIV to enhancing weight loss. Alpha-lipoic acid may have been combined with other plants or extracts in a specific preparation to treat … (ii) Alpha-lipoic acid is a powerful antioxidant that regenerates other antioxidants (e.g., vitamins E and C, and reduced glutathione) and has metal-chelating activity. "ALA should be admitted at least 2 hr after eating or if taken before; meal should be taken at least 30 min after ALA administration In addition, it has been suggested that acidic pH of the stomach is favorable for ALA absorption through the gastrum. … Alpha lipoic acid (ALA), also known as thioctic acid, is an eight-carbon organosulfur compound derived from caprylic acid (octenoic acid). You get small amounts of lipoic acid in your diet from spinach and collard greens, broccoli, beef and organ meats. The selenide ion forms an extremely stable, insoluble compound with mercury, and provides relief of mercurialism symptoms. This increased influx of tryptophan has been shown to result in an increase in serotonin synthesis. Press J to jump to the feed. Optim-ALA Optimized Alpha Lipoic Acid should provide and support optimal mitochondrial function, energy … Alpha-lipoic acid is an antioxidant that's in many foods, and it's made naturally in our bodies. A friend was telling me about the antioxidant Alpha Lipoic Acid (ALA), and talking about how it can have anti-inflammatory effects. A selenium yeast product increased mercury excretion and decreased oxidative stress-related biomarkers, particularly urinary malondialdehyde and 8-hydroxy-2-deoxyguanosine [63]. ALA has been widely explored as a beneficial nutrient for a variety of bodily functions involving the nervous, cardiovascular, immune and detoxification systems. Press question mark to learn the rest of the keyboard shortcuts, Lipoic Acid as a potential chelator for mercury, the literature shows a half-life of just over 30 minutes. Nonetheless, people claim moderate success using his regimen. Some folks say it helps as it acts as a glucose disposal agent, thus allowing slightly higher carb consumption without exiting ketosis. Alpha lipoic acid has helped me muscle twitches & neuropathy tremendously. (iii) Given that toxic metals have a great affinity for sulfur-containing peptides, diets rich in sulfur-containing foods, such as alliums (e.g. Ala it needs for these purposes symptoms of diabetes and the management of diabetic nerve pain, 650. And collard greens, broccoli, liver, kidney, and worrying memory.. Acid ( LA ), and eye Health of time and saw no.... Her memory problems vanished completely heavy metals Much higher doses for way longer periods of time and saw change... 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